Methanol → 2,2,6,6-Tetramethyl-4-piperidone

HRID 1658310ノート

反応式

HRID 1658310 の反応式
[CH3:1][C:2]1[CH2:7][C:6]([CH3:9])([CH3:8])[NH:5][C:4]([CH3:11])([CH3:10])N=1.CO.[N+]([O-])(O)=[O:15].NC(N)=O>CC(C)=O>[CH3:10][C:4]1([CH3:11])[NH:5][C:6]([CH3:9])([CH3:8])[CH2:7][C:2](=[O:15])[CH2:1]1

参加物

5

反応物 3

HCID 887MethanolHCID 31295Urea nitrateHCID 68396Acetonin

生成物 1

HCID 132202,2,6,6-Tetramethyl-4-piperidone収率 125%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A solution of 5.0 g. of acetonine in 21 g. of methanol was added with 19 g. of acetone and 4.0 g. of urea nitrate. The mixture was maintained at room temperature for 24 hours to effect the reaction. After completion of the reaction, the reaction mixture was purified in the same manner as in Example 1 to obtain triacetonamine in a yield of 125%.

後処理

  1. customthe reaction
  2. customAfter completion of the reaction
  3. customthe reaction mixture was purified in the same manner as in Example 1

出典と根拠

ORDレコード
ord-40089d1652a641c88c7a98a3bfbd95a6
出典データセット
uspto-grants-1976_06
特許番号
US03963730

反応ノート

読み込み中…