Sulfuric Acid → 51264-33-6

反応式

[Na].[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([C:21]2[CH:26]=[CH:25][C:24]([O:27][S:28]([OH:31])(=[O:30])=[O:29])=[CH:23][CH:22]=2)([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)C(OCC)=O)=[CH:5][CH:4]=1.[OH-].[Na+].S(=O)(=O)(O)O.[Na].N1C=CC=CC=1C>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]([C:21]2[CH:26]=[CH:25][C:24]([O:27][S:28]([OH:31])(=[O:30])=[O:29])=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)=[CH:7][CH:8]=1

参加物

反応物 4

HCID 1118Sulfuric Acid

HCID 14798Sodium Hydroxide

HCID 86733562HCID 86733562、化合物

HCID 86733563HCID 86733563、化合物

生成物 1

HCID 20858251264-33-6

実験手順

20 g. ethyl α-(4-hydroxyphenyl)-α-(4-sulphoxyphenyl)-2-pyridine-acetate monosodium salt were dissolved in 200 ml. 3% aqueous sodium hydroxide solution and the solution then boiled for 1 hour. After cooling, the pH was adjusted to 7.5 by adding diluted sulphuric acid and then distilled to dryness. The residue was treated with boiling ethanol and insoluble material was filtered off. The ethanol extract was concentrated to a small volume to give, by crystallisation, a high yield of the desired 4-hydroxyphenyl-4-sulphoxyphenyl-(2-pyridyl-methane monosodium salt in the form of colourless crystals which melted at 197° - 199°C. (decomposition).