HCID 4163245、化合物 → N-Phenethyl-benzene-1,4-diamine

HRID 1658447ノート

反応式

HRID 1658447 の反応式
[C:1]1([CH2:7][CH2:8][NH:9][C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H][H]>[Pd].CO>[C:1]1([CH2:7][CH2:8][NH:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 2

HCID 4163245HCID 4163245、化合物HCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 2316538N-Phenethyl-benzene-1,4-diamine

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

A mixture of 15 g. of N-(2-phenylethyl)-p-nitroaniline, 100 ml. of methanol, and 2.5 g. of 10% palladium on carbon catalyst is shaken under 1 to 2 atmospheres of hydrogen until uptake of the hydrogen ceases. The resultant reaction mixture is filtered through celite and washed with methanol. The filtrate is concentrated in vacuo to yield the product, N-(2-phenylethyl)-p-phenylenediamine, as an oil which can be converted to the dihydrochloride, m.p. 247°C. by bubbling hydrogen chloride gas through a solution of the oil in ether for 1/2 hour.

後処理

  1. additionA mixture of 15 g
  2. customThe resultant reaction mixture
  3. filtrationis filtered through celite
  4. washwashed with methanol
  5. concentrationThe filtrate is concentrated in vacuo

出典と根拠

ORDレコード
ord-dcc239e5b37b435fb91370e08c32847e
出典データセット
uspto-grants-1976_06
特許番号
US03963780

反応ノート

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