4-Toluenesulfonyl chloride → HCID 53828981、化合物

HRID 1659895ノート

反応式

HRID 1659895 の反応式
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[Cl:12][C:13]1[C:14]([Cl:25])=[CH:15][C:16]2[O:21][CH2:20][CH2:19][C:18](=[N:22][OH:23])[C:17]=2[CH:24]=1>N1C=CC=CC=1>[Cl:12][C:13]1[C:14]([Cl:25])=[CH:15][C:16]2[O:21][CH2:20][CH2:19][C:18](=[N:22][O:23][S:7]([C:4]3[CH:5]=[CH:6][C:1]([CH3:11])=[CH:2][CH:3]=3)(=[O:9])=[O:8])[C:17]=2[CH:24]=1

参加物

4

反応物 2

HCID 73974-Toluenesulfonyl chlorideHCID 857730826,7-Dichloro-2,3-dihydro-4-(hydroxyimino)-4H-1-benzopyran

生成物 1

HCID 53828981HCID 53828981、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒2 回

実験手順

A solution of p-toluenesulfonyl chloride (103 g) in 125 ml pyridine was added dropwise at 5°-10° to 6,7-dichloro-2,3-dihydro-4-(hydroxyimino)-4H-1-benzopyran (62.5 g) in 250 ml pyridine. The reaction mixture was then stirred for 20 hours at room temperature, poured into ice-water to separate out the title compound, which was filtered, washed several times with water, then once with ether, and finally dried in air. Yield: 101.8 g; m.p. 180°-184°.

後処理

  1. customto separate out the title compound, which
  2. filtrationwas filtered
  3. washwashed several times with water
  4. dry with materialonce with ether, and finally dried in air

出典と根拠

ORDレコード
ord-19303a9928b9407aac4fb177cf7d67be
出典データセット
uspto-grants-1981_12
特許番号
US04305954

反応ノート

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