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Thionyl Chloride → 8-Methoxy-1,4-benzodioxane-5-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 8-Methoxy-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic Acid | HCID 22734248 | — |
| 生成物 | 8-Methoxy-1,4-benzodioxane-5-carbonyl chloride | HCID 20544710 | 100.6% |
反応手順
391 g of thionyl chloride and 138 g of 8-methoxy-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated to 50°-55° C. and the excess thionyl chloride was distilled off under vacuum. 151 g of 8-methoxy-1,4-benzodioxane-5-carbonyl chloride were obtained (yield: 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04306072 |
| 出典データセット | uspto-grants-1981_12 |
| ORD ID | ord-92993792b1a942c2907a131ffdc84638 |
| 出典メモ | uspto-grants-1981_12 |