反应详情

391 g of thionyl chloride and 138 g of 8-methoxy-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated to 50°-55° C. and the excess thionyl chloride was distilled off under vacuum. 151 g of 8-methoxy-1,4-benzodioxane-5-carbonyl chloride were obtained (yield: 100%).

1. customprovided with a condenser
2. temperatureThe mixture was heated to 50°-55° C.
3. distillationthe excess thionyl chloride was distilled off under vacuum