2-Naphthol → 1,8-Bis (2-naphthoxy) octane

HRID 1660109ノート

反応式

HRID 1660109 の反応式
[Na].[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[OH:12].BrCCCCCCCCBr.[CH:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][C:24]=1[O:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41]>>[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][O:33][C:24]1[CH:25]=[CH:26][C:27]2[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:23]=1

参加物

5

反応物 4

HCID 86632-NaphtholHCID 783101,8-DibromooctaneHCID 5360545SodiumHCID 14718441HCID 14718441、化合物

生成物 1

HCID 130554851,8-Bis (2-naphthoxy) octane

実験手順

Using the method described in Example 1, the crude solids were prepared using 5.5 g (0.24 gram atoms) sodium metal, 34.6 g (0.24 mole) 2-naphthol, and 27.2 g (0.100 mole) 1,8-dibromooctane. Recrystallization from ethyl acetate gave 30.0 g, mp 128° C., and 0.8 g, mp 125°-126° C., of pure 1,8-bix (2-naphthoxy) octane. The NMR spectrum was consistent with the structure and showed the absence of impurities.

後処理

  1. customthe crude solids were prepared
  2. customRecrystallization from ethyl acetate
  3. customgave 30.0 g, mp 128° C., and 0.8 g, mp 125°-126° C.

出典と根拠

ORDレコード
ord-911d231d6fb646a1a98f5ef0c38c40d4
出典データセット
uspto-grants-1981_12
特許番号
US04307077

反応ノート

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