Diethyl Ether → 3-[2-(2,5-Dimethyl-pyrrol-1-yl)-4-trifluoromethyl-thiazol-5-yl]-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine

反応式

Br[C:2]1[S:6][C:5]([N:7]2[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[CH3:13])=[N:4][C:3]=1[C:14]([F:17])([F:16])[F:15].C([Li])(C)(C)C.[CH2:23]([CH:25]([C:28]1[N:33]2[N:34]=[C:35]([CH3:38])[C:36](I)=[C:32]2[N:31]=[C:30]([CH3:39])[CH:29]=1)[CH2:26][CH3:27])[CH3:24].C(OCC)C>C1COCC1.[Cl-].[Zn+2].[Cl-].CC(C)([P](C(C)(C)C)([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)C(C)(C)C)C>[CH3:13][C:8]1[N:7]([C:5]2[S:6][C:2]([C:36]3[C:35]([CH3:38])=[N:34][N:33]4[C:28]([CH:25]([CH2:23][CH3:24])[CH2:26][CH3:27])=[CH:29][C:30]([CH3:39])=[N:31][C:32]=34)=[C:3]([C:14]([F:17])([F:16])[F:15])[N:4]=2)[C:11]([CH3:12])=[CH:10][CH:9]=1