5-Methylthiazole → [1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(5-methyl-thiazol-2-yl)-methanone

HRID 1661231ノート

反応式

HRID 1661231 の反応式
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=3[O:24][CH3:25])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5].[CH3:27][C:28]1[S:32][CH:31]=[N:30][CH:29]=1>>[F:23][C:21]1[CH:20]=[CH:19][C:18]([O:24][CH3:25])=[C:17]([C:13]2[CH:14]=[CH:15][CH:16]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:31]4[S:32][C:28]([CH3:27])=[CH:29][N:30]=4)=[O:5])[N:7]=[CH:8]3)[CH:12]=2)[CH:22]=1

参加物

3

反応物 2

HCID 1379805-MethylthiazoleHCID 866344281-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amide

生成物 1

HCID 67431632[1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(5-methyl-thiazol-2-yl)-methanone

実験手順

This compound was prepared by method C using compound 12b and 5-methylthiazole.

後処理

  1. customThis compound was prepared by method C

出典と根拠

ORDレコード
ord-b34d07a003ea43199809f6bf0cd50e39
出典データセット
uspto-grants-2011_10
特許番号
US08030339B2

反応ノート

読み込み中…