2,3-Dihydroxybutanedioic Acid → HCID 178418492、化合物

HRID 1663

反応式

HRID 1663 の反応式
[C:1]([OH:10])(=[O:9])[CH:2]([CH:4]([C:6]([OH:8])=[O:7])[OH:5])[OH:3].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]([O:21][C@H:22]2[CH2:27][CH2:26][C@H:25]([C:28]3[CH:33]=[CH:32][C:31]([CH2:34][N:35]([CH3:37])[CH3:36])=[CH:30][CH:29]=3)[CH2:24][CH2:23]2)=[O:20])=[CH:14][CH:13]=1.C(OCC)C>C(O)C>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]([O:21][C@H:22]2[CH2:23][CH2:24][C@H:25]([C:28]3[CH:29]=[CH:30][C:31]([CH2:34][N:35]([CH3:36])[CH3:37])=[CH:32][CH:33]=3)[CH2:26][CH2:27]2)=[O:20])=[CH:14][CH:13]=1.[C:6]([CH:4]([CH:2]([C:1]([O-:10])=[O:9])[OH:3])[OH:5])([O-:8])=[O:7]

参加物

5

反応物 3

HCID 8752,3-Dihydroxybutanedioic AcidHCID 3283Diethyl EtherHCID 178418347HCID 178418347、化合物

生成物 1

HCID 178418492HCID 178418492、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

First 0.15 g (0.001 mol) of anhydrous tartaric acid and then 0.39 g (0.001 mol) of trans-O-(4-chlorophenylacetyl)-4-(4-dimethylaminomethylphenyl)-cyclohexanol are dissolved in 7 ml of absolute ethanol. Diethyl ether is then added to the clear solution until it becomes slightly cloudy and it is then left to stand for 8 hours at +4° C. The crystalline product precipitated is suction filtered, washed with diethyl ether and dried.

後処理

  1. waitit is then left
  2. customThe crystalline product precipitated
  3. filtrationfiltered
  4. washwashed with diethyl ether
  5. customdried

出典と根拠

ORDレコード
ord-55aacc7a80b0419cab9d2c65fa6adadb
出典データセット
uspto-grants-1998_03
特許番号
US05726205

関連ノート

読み込み中…