4-(Dimethylsulfamoyl)benzoic acid → 4-(N,N-dimethylsulfamoyl)benzoyl chloride
反応式
[CH3:1][N:2]([CH3:15])[S:3]([C:6]1[CH:14]=[CH:13][C:9]([C:10](O)=[O:11])=[CH:8][CH:7]=1)(=[O:5])=[O:4].S(Cl)([Cl:18])=O>>[CH3:1][N:2]([CH3:15])[S:3]([C:6]1[CH:14]=[CH:13][C:9]([C:10]([Cl:18])=[O:11])=[CH:8][CH:7]=1)(=[O:5])=[O:4]参加物
3
反応条件
- 温度
- 90 °C
実験手順
A mixture of 4-dimethylsulfamoylbenzoic acid (688 mg) and thionyl chloride (5 mL) was stirred at 90° C. overnight. The reaction mixture was concentrated to give 4-dimethylsulfamoylbenzoyl chloride (495 mg) as a white solid.
後処理
- concentrationThe reaction mixture was concentrated
出典と根拠
- ORDレコード
- ord-1c041bcb11874842a97474a2a3d7458c
- 出典データセット
- uspto-grants-2011_10
- 特許番号
- US08034949B2
反応ノート
読み込み中…