2-Naphthyl isopropyl ketone → alpha-Bromoisopropyl 2-naphthyl ketone

HRID 1664097ノート

反応式

HRID 1664097 の反応式
[Br-:1].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.[CH:34]([C:37]([C:39]1[CH:48]=[CH:47][C:46]2[C:41](=[CH:42][CH:43]=[CH:44][CH:45]=2)[CH:40]=1)=[O:38])([CH3:36])[CH3:35]>O1CCCC1>[CH:40]1[C:41]2[C:46](=[CH:45][CH:44]=[CH:43][CH:42]=2)[CH:47]=[CH:48][C:39]=1[C:37]([C:34]([Br:1])([CH3:36])[CH3:35])=[O:38]

参加物

4

反応物 2

HCID 109654952-Naphthyl isopropyl ketoneHCID 17977687Phenyltrimethylammonium bromide dibromide

生成物 1

HCID 12587407alpha-Bromoisopropyl 2-naphthyl ketone収率 172.2%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

2.16 g of phenyltrimethylammonium tribromide was added to a mixture comprising 1.14 g of 2-naphthyl isopropyl ketone and 25 ml of tetrahydrofuran, and the mixture was reacted at room temperature for 3 hours. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 1.59 g of oily α-bromoisopropyl 2-naphthyl ketone.

後処理

  1. customthe mixture was reacted at room temperature for 3 hours
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-8037e13c8f1c4a26a0fd6316a351b37f
出典データセット
uspto-grants-2011_10
特許番号
US08039420B2

反応ノート

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