反応式
C1C=NC2C(N=1)=CC1C3CNCC(C=1C=2)C3.[S:17]([C:21]1[CH:27]=[CH:26][C:24]([CH3:25])=[CH:23][CH:22]=1)([O-:20])(=[O:19])=[O:18].C1C=NC2C(N=1)=CC1C3CNCC(C=1C=2)C3>>[C:24]1([CH3:25])[CH:23]=[CH:22][C:21]([S:17]([OH:20])(=[O:18])=[O:19])=[CH:27][CH:26]=1参加物
3
実験手順
Varenicline Tosylate can be prepared by combining Varenicline base, a solvent and p-Toluene sulfonic acid (p-TSA) to obtain a reaction mixture and precipitating Varenicline Tosylate from the reaction mixture. Preferably, the obtained Varenicline Tosylate is further recovered from the reaction mixture.
出典と根拠
- ORDレコード
- ord-a043c6acb8064c67afa11162b50f2adf
- 出典データセット
- uspto-grants-2011_10
- 特許番号
- US08039620B2
関連ノート
読み込み中…