1-(4-(6-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea → 1-(4-(2-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea

反応式

[CH3:1][O:2][C:3]1[CH:38]=[CH:37][C:6]([CH2:7][NH:8][C:9]2[N:14]=[C:13]([O:15]C3C=CC(NC(=O)CC(NC4C=CC(F)=CC=4)=O)=CC=3F)[CH:12]=[CH:11][N:10]=2)=[CH:5][CH:4]=1.FC1C=CC(CC(N=C=O)=O)=CC=1.COC1C=CC(CNC2N=CN=C(O[C:67]3[CH:72]=[CH:71][C:70]([NH:73][C:74]([NH:76][C:77](=[O:86])[CH2:78][C:79]4[CH:84]=[CH:83][C:82]([F:85])=[CH:81][CH:80]=4)=[O:75])=[CH:69][C:68]=3[F:87])C=2)=CC=1>C1COCC1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][NH:8][C:9]2[N:14]=[C:13]([O:15][C:67]3[CH:72]=[CH:71][C:70]([NH:73][C:74]([NH:76][C:77](=[O:86])[CH2:78][C:79]4[CH:84]=[CH:83][C:82]([F:85])=[CH:81][CH:80]=4)=[O:75])=[CH:69][C:68]=3[F:87])[CH:12]=[CH:11][N:10]=2)=[CH:37][CH:38]=1