HCID 67343100、化合物 → HCID 57879609、化合物
反応式
[C:1]([NH:9][C:10]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[C:25]([Cl:30])[CH:24]=2)[CH:20]=[CH:19][C:11]=1[C:12]([O:14]C(C)(C)C)=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>FC(F)(F)C(O)=O>[C:1]([NH:9][C:10]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[C:25]([Cl:30])[CH:24]=2)[CH:20]=[CH:19][C:11]=1[C:12]([OH:14])=[O:13])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
3
実験手順
10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(3-chloro-4-hydroxyphenyl)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and toluene was added. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 94 mg of 2-(benzamido)-4-(3-chloro-4-hydroxyphenyl)benzoic acid as white solid.
後処理
- customThe solvent was evaporated under reduced pressure and toluene
- additionwas added
- customThe solvent was evaporated under reduced pressure and diisopropyl ether