Trifluoroacetic acid → HCID 57879592、化合物
反応式
FC(F)(F)C(O)=O.[C:8]([NH:16][C:17]1[CH:29]=[C:28]([C:30]2[CH:35]=[CH:34][C:33]([CH3:36])=[C:32]([Cl:37])[CH:31]=2)[CH:27]=[CH:26][C:18]=1[C:19]([O:21]C(C)(C)C)=[O:20])(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:8]([NH:16][C:17]1[CH:29]=[C:28]([C:30]2[CH:35]=[CH:34][C:33]([CH3:36])=[C:32]([Cl:37])[CH:31]=2)[CH:27]=[CH:26][C:18]=1[C:19]([OH:21])=[O:20])(=[O:15])[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1参加物
3
実験手順
5.0 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(3-chloro-4-Methylphenyl)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and methanol was added to the obtained residue and a solid substance was separated by filtration to obtain 14 mg of 2-(benzamido)-4-(3-chloro-4-methylphenyl)benzoic acid as white solid.
後処理
- customThe solvent was evaporated under reduced pressure and methanol
- additionwas added to the obtained residue
- customa solid substance was separated by filtration