Tert-butyl 2-(3,5-dichlorobenzamido)-4-phenethylbenzoate → 2-(3,5-Dichlorobenzamido)-4-phenethylbenzoic acid
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:29]=[C:30]([Cl:32])[CH:31]=1)[C:5]([NH:7][C:8]1[CH:20]=[C:19]([CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:18]=[CH:17][C:9]=1[C:10]([O:12]C(C)(C)C)=[O:11])=[O:6]>FC(F)(F)C(O)=O>[Cl:1][C:2]1[CH:3]=[C:4]([CH:29]=[C:30]([Cl:32])[CH:31]=1)[C:5]([NH:7][C:8]1[CH:20]=[C:19]([CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:18]=[CH:17][C:9]=1[C:10]([OH:12])=[O:11])=[O:6]参加物
3
実験手順
10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(3,5-dichlorobenzamido)-4-phenethylbenzoate and stirred ad room temperature for 2 hours. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 62 mg of 2-(3,5-dichlorobenzamido)-4-phenethylbenzoic acid as white solid.
後処理
- customThe solvent was evaporated under reduced pressure and diisopropyl ether