Aluminum(III) Chloride → 2-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone

HRID 1679705ノート

反応式

HRID 1679705 の反応式
[CH2:1]([C:3]1([CH2:17][CH2:18][CH3:19])[CH2:11][C:10]2[C:5](=[C:6]([Cl:15])[C:7]([Cl:14])=[C:8]([O:12]C)[CH:9]=2)[C:4]1=[O:16])[CH3:2].[Cl-].[Al+3].[Cl-].[Cl-]>CCCCCCC>[CH2:1]([C:3]1([CH2:17][CH2:18][CH3:19])[CH2:11][C:10]2[C:5](=[C:6]([Cl:15])[C:7]([Cl:14])=[C:8]([OH:12])[CH:9]=2)[C:4]1=[O:16])[CH3:2]

参加物

4

反応物 2

HCID 6451240Aluminum(III) ChlorideHCID 123955632-Ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone

生成物 1

HCID 123955852-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone

試薬・触媒・溶媒 1

HCID 8900Heptane溶媒

実験手順

2-Ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone is prepared following substantially the same procedure described in Example 5, Step F, using the following substances: 2-ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone (11 g., .037 mole), aluminum chloride (12.5 g., 0.094 mole) and heptane (400 ml.). The above procedure gives 9.0 g. of 2-ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone which after recrystallization from methylcyclohexane melts at 153° C.

後処理

  1. customThe above procedure gives 9.0 g
  2. customof 2-ethyl-2-n-propyl-5-hydroxy-6,7-dichloro-1-indanone which after recrystallization from methylcyclohexane melts at 153° C.

出典と根拠

ORDレコード
ord-14bb8336af204d30a5ee0a896ae3fab7
出典データセット
uspto-grants-1978_03
特許番号
US04081554

反応ノート

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