HCID 86735590、化合物 → HCID 131711063、化合物
反応式
[CH3:1][O:2][C:3](=[O:26])[CH2:4][NH:5][C:6](=[O:25])[C@H:7]([CH3:24])[NH:8][C:9](=[O:23])[CH2:10][NH:11][C:12](=[O:22])[CH2:13][NH:14]C(OC(C)(C)C)=O>FC(F)(F)C(O)=O>[NH2:14][CH2:13][C:12]([NH:11][CH2:10][C:9]([NH:8][C@H:7]([C:6]([NH:5][CH2:4][C:3]([O:2][CH3:1])=[O:26])=[O:25])[CH3:24])=[O:23])=[O:22]参加物
3
実験手順
A solution of Boc-Gly-Gly-Ala-Gly-OMe (2.0 g, 5.35 mmole, described in Example 4) in trifluoroacetic acid (25 ml) is stirred at 0° C for 1 hr. The solvent is evaporated, the residue triturated with ether, the solid collected and dried to give the tetrapeptide of formula H-Gly-Gly-Ala-Gly-OMe isolated as the trifluoroacetic acid addition salt.
後処理
- customThe solvent is evaporated
- customthe residue triturated with ether
- customthe solid collected
- customdried
出典と根拠
- ORDレコード
- ord-02038cc34023458b96bf99db2fa0291c
- 出典データセット
- uspto-grants-1978_03
- 特許番号
- US04081530
反応ノート
読み込み中…