Hydrazine hydrate (1:1) → 6-Hydrazinyl-5-methoxy-3-pyridinesulfonamide
反応式
Cl[C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:4][N:3]=1.O.[NH2:15][NH2:16]>CO>[NH:15]([C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:4][N:3]=1)[NH2:16]参加物
4
実験手順
2-Chloro-3-methoxy-5-sulfamoylpyridine (0.3 g, 1.35×10-3 mole) and hydrazine hydrate (0.53 g, approximately 0.01 mole) were added to methanol (20 ml). After refluxing overnight, the reaction mixture was stripped of methanol in vacuo to yield an oil which was cooled in an ice bath and triturated with water (5 ml). The precipitate was collected by filtration and air dried; yield, 0.22 g (75 percent).
後処理
- temperatureAfter refluxing overnight
- customto yield an oil which
- temperaturewas cooled in an ice bath
- customtriturated with water (5 ml)
- filtrationThe precipitate was collected by filtration and air
- customdried
- customyield
出典と根拠
- ORDレコード
- ord-608a8918b7ad4a2e8c10452b88540f13
- 出典データセット
- uspto-grants-1981_06
- 特許番号
- US04273706
反応ノート
読み込み中…