Sodium Azide → Tert-butyl 3-azidocyclopentanoate
反応式
[N-:1]=[N+:2]=[N-:3].[Na+].S([O-])(=O)(=O)C.S(O[CH:15]1[CH2:19][CH2:18][CH:17]([C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:16]1)(C)(=O)=O>O>[N:1]([CH:19]1[CH2:15][CH2:16][CH:17]([C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:18]1)=[N+:2]=[N-:3]参加物
5
実験手順
Sodium azide (156 mg) was added to the mesylate [prepared in (1) ]dissolved in hexamethylphosphamide (3 ml). The mixture was poured into water. The mixture was extracted with ethyl acetate. The extract was washed with water, dried over magnesium sulfate and then evaporated to obtain the title compound having the following physical data.
後処理
- extractionThe mixture was extracted with ethyl acetate
- washThe extract was washed with water
- dry with materialdried over magnesium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-9e9ebfdaaa1d4977beaff1ebf5a15d0f
- 出典データセット
- uspto-grants-1992_12
- 特許番号
- US05168101
反応ノート
読み込み中…