Ethanol → 4-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

反応式

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH:12](CC)[CH2:13]N3C(=O)C4C(=CC=CC=4)C3=O)[CH:11]=2)[CH:2]=1.O.[NH2:28]N.[CH2:30](O)[CH3:31]>>[CH:5]1[CH:6]=[N:1][CH:2]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH2:12][CH2:13][CH2:30][CH2:31][NH2:28])[CH:11]=2)[CH:4]=1

参加物

反応物 3

HCID 702Ethanol

HCID 24654Hydrazine hydrate (1:1)

HCID 186948072-(4-(3-pyridinyl)-1H-imidazol-1-yl)-butyl-1H-iso-indol-1,3(2H)-dione

生成物 1

HCID 110421604-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

実験手順

Using the procedure of Stage B of Example 1, 1.66 g of the product of Stage A and 0.46 ml of hydrazine hydrate in 30 ml of ethanol were reacted to obtain 936 mag of the desired product which was used as is for the synthesis.

後処理

customwere reacted

出典と根拠

ORDレコード: ord-deef02374e4b4015adfe8eaec2a1920c
出典データセット: uspto-grants-1997_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05635485

反応ノート

読み込み中…