Hydrazine hydrate (1:1) → 4-Hydrazinylpyridin-2(1H)-one
反応式
[OH:1][C:2]1[CH:7]=[C:6](O)[CH:5]=[CH:4][N:3]=1.O.[NH2:10][NH2:11]>COCCO>[NH:10]([C:6]1[CH:5]=[CH:4][NH:3][C:2](=[O:1])[CH:7]=1)[NH2:11]参加物
4
実験手順
2,4-dihydroxypyridine (20.3 g, 183.0 mmol) was added to the mixture of 2-methoxyethanol (400 ml) and 55% solution of hydrazine hydrate (80 ml) at room temperature. The reaction mixture was refluxed under stirring for 24 hours and then concentrated under reduced pressure. The resulting residue was recrystallized with ethanol to give the titled compound as a white solid. (Yield: 88.3%)
後処理
- temperatureThe reaction mixture was refluxed
- concentrationconcentrated under reduced pressure
- customThe resulting residue was recrystallized with ethanol
出典と根拠
- ORDレコード
- ord-7083380ba142451c9192d036c6168634
- 出典データセット
- uspto-grants-2012_04
- 特許番号
- US08148529B2
反応ノート
読み込み中…