反応式
[CH3:1][C:2](=[O:6])[CH:3]=[CH:4][CH3:5].Cl[Mg][CH2:9][Si:10]([CH3:13])([CH3:12])[CH3:11]>C(OCC)C>[CH3:5][CH:4]([CH2:9][Si:10]([CH3:13])([CH3:12])[CH3:11])[CH2:3][C:2](=[O:6])[CH3:1]参加物
4
実験手順
A solution of 8.00 g pent-3-en-2-one in 50 mL dry diethyl ether was dropped to a solution of 73.5 mL of chloro[(trimethylsilyl)methyl]magnesium (1.0M in diethyl ether) and 955 mg of CuBr at −5° C. under Argon. The mixture was stirred for 1 hour at room temperature. An aqueous work-up followed by silica gel chromatography yielded 5.20 g (43%) of a colourless oil.
出典と根拠
- ORDレコード
- ord-4a4bf6f84aee42c39db133cf56d29530
- 出典データセット
- uspto-grants-2012_04
- 特許番号
- US08148538B2
関連ノート
読み込み中…