Water → Benzaldehyde, 2,6-dichloro-, oxime

HRID 1689797

反応式

HRID 1689797 の反応式
C(N(CC)CC)C.[Cl:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:10]=1[CH:11]=O.Cl.[NH2:19][OH:20].O>ClCCl>[Cl:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:10]=1[CH:11]=[N:19][OH:20]

参加物

6

反応物 4

HCID 962WaterHCID 67372,6-DichlorobenzaldehydeHCID 8471TriethylamineHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 91328Benzaldehyde, 2,6-dichloro-, oxime収率 132.9%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Alternate procedure: Add triethylamine (23.1 g, 229 mmol) dropwise to a solution of 2,6-dichloro-benzaldehyde (20.0 g, 114 mmol) and hydroxylamine hydrochloride (10.3 g, 149 mmol) in dichloromethane (200 mL). Stir the reaction mixture for 8 h. Add water (200 mL). Separate the phases and extract the aqueous phase with dichloromethane (100 mL). Wash the combined organic phases with water (100 mL). Concentrate the combined organic phases to provide 28.8 g (94%) of the title compound.

後処理

  1. customSeparate the phases
  2. extractionextract the aqueous phase with dichloromethane (100 mL)
  3. washWash the combined organic phases with water (100 mL)
  4. concentrationConcentrate the combined organic phases

出典と根拠

ORDレコード
ord-868f23b784d94cea9d97e1fd57aa73cf
出典データセット
uspto-grants-2012_04
特許番号
US08153624B2

関連ノート

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