6-Nitroquinolin-5-ylamine → Quinoline-5,6-diamine
反応式
[NH2:1][C:2]1[C:11]([N+:12]([O-])=O)=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2>[Pd].CCO>[NH2:1][C:2]1[C:11]([NH2:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2参加物
4
実験手順
A mixture of 5-Amino-6-nitroquinoline (650 mg, 3.44 mmol), Pd/C (70 mg) and 15 mL of EtOH was stirred under H2 (balloon) overnight. The reaction mixture was filtered through Celite and the filtrate was concentrated to give 5,6-diaminoquinoline.
後処理
- filtrationThe reaction mixture was filtered through Celite
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-291f51b0392641508c6389841d1f93e1
- 出典データセット
- uspto-grants-2012_04
- 特許番号
- US08153626B2
反応ノート
読み込み中…