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8-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine → HCID 178488351、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 8-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine | HCID 22147356 | — |
| 反応物 | tert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane | HCID 46855450 | — |
| 生成物 | HCID 178488351 | HCID 178488351 | 79.2% |
反応手順
Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (2.76 g, 8.5 mmol; HPLC: 4.446 min) and rac-8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylamine (CAS 535935-61-6) (1.51 g, 8.5 mmol; HPLC 0.403 min) according to the procedure described for Example 1. Obtained the title compound as a yellow solid (2.38 g, 79%, HPLC 1.805 min), MS (ISP) m/e=354.2 [(M+H)+].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08163740B2 |
| 出典データセット | uspto-grants-2012_04 |
| ORD ID | ord-1a8c8f06ae1c45b6a1abc6fc6bacf75f |
| 出典メモ | uspto-grants-2012_04 |