HCID 58255767、化合物 → HCID 58255762、化合物
反応式
[N+:1]([C:4]1[C:5]2[C:9]([CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH:20]4[CH2:25][CH2:24][CH2:23][CH2:22][O:21]4)[CH:14]=3)[CH:12]=1)=[N:8][N:7]([CH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][O:27]1)[CH:6]=2)([O-])=O>C(OCC)(=O)C.[Pd]>[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31][CH:26]1[N:7]1[CH:6]=[C:5]2[C:9]([CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH:20]4[CH2:25][CH2:24][CH2:23][CH2:22][O:21]4)[CH:14]=3)[CH:12]=[C:4]2[NH2:1])=[N:8]1参加物
4
実験手順
4-Nitro-2-(tetrahydro-2H-pyran-2-yl)-6-[3-(tetrahydro-2H-pyran-2-yloxy)phenyl]-2H-indazole (1.06 g, 2.5 mmol) was dissolved in ethyl acetate (100 ml) and 10% Pd/C (53 mg) was added. The reaction was stirred under an atmosphere of hydrogen gas (1 atm) at RT for 16 h. The reaction mixture was filtered through celite and the solvent was removed in vacuo to yield the title compound, 828 mg, used without further purification.
後処理
- filtration