Sodium Carbonate → N-[6-(5-Amino-6-chloro-3-pyridinyl)-2-(tetrahydro-2H-pyran-2-yl)-2H-indazol-4-yl]-2-methyl-1,3-thiazole-4-carboxamide

反応式

[CH3:1][C:2]1[S:3][CH:4]=[C:5]([C:7]([NH:9][C:10]2[C:11]3[C:15]([CH:16]=[C:17](B4OC(C)(C)CC(C)(C)O4)[CH:18]=2)=[N:14][N:13]([CH:29]2[CH2:34][CH2:33][CH2:32][CH2:31][O:30]2)[CH:12]=3)=[O:8])[N:6]=1.Br[C:36]1[CH:37]=[C:38]([NH2:43])[C:39]([Cl:42])=[N:40][CH:41]=1.C(=O)([O-])[O-].[Na+].[Na+].O1CCOCC1>C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].O>[NH2:43][C:38]1[CH:37]=[C:36]([C:17]2[CH:18]=[C:10]([NH:9][C:7]([C:5]3[N:6]=[C:2]([CH3:1])[S:3][CH:4]=3)=[O:8])[C:11]3[C:15]([CH:16]=2)=[N:14][N:13]([CH:29]2[CH2:34][CH2:33][CH2:32][CH2:31][O:30]2)[CH:12]=3)[CH:41]=[N:40][C:39]=1[Cl:42]