HCID 1486231、化合物 → 6-Oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid
反応式
Cl[C:2]1[C:3]([C:15]([OH:17])=[O:16])=[N:4][N:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:6](=[O:8])[CH:7]=1>CCO.[Pd]>[O:8]=[C:6]1[N:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:4]=[C:3]([C:15]([OH:17])=[O:16])[CH:2]=[CH:7]1参加物
4
実験手順
4-chloro-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid (100 mg, 0.4 mmol) was dissolved in 3 ml EtOH and Pd/C (25 mg) was added. A H2 balloon was attached to the reaction vessel and the mixture was stirred for 4 h. The reaction was filtered through a pad of Celite®, concentrated and used without further purification in the next reaction. MS m/z: 217(100%, M+1)).
後処理
- filtrationThe reaction was filtered through a pad of Celite®
- concentrationconcentrated
- customused without further purification in the next reaction
出典と根拠
- ORDレコード
- ord-b1b7533d7e6743e387ccf75387f1060b
- 出典データセット
- uspto-grants-2012_04
- 特許番号
- US08163766B2
反応ノート
読み込み中…