Piperonal → Bis(3,4-methylenedioxy)chalcone

HRID 1698450

反応式

HRID 1698450 の反応式
[CH:1]1[C:6]([CH:7]=[O:8])=[CH:5][C:4]2[O:9][CH2:10][O:11][C:3]=2[CH:2]=1.[CH3:12][C:13]([C:15]1[CH:20]=[CH:19][C:18]2[O:21][CH2:22][O:23][C:17]=2[CH:16]=1)=O.[OH-].[Na+]>C(O)C>[CH2:22]1[O:21][C:18]2[CH:19]=[CH:20][C:15]([CH:13]=[CH:12][C:7]([C:6]3[CH:1]=[CH:2][C:3]4[O:11][CH2:10][O:9][C:4]=4[CH:5]=3)=[O:8])=[CH:16][C:17]=2[O:23]1

参加物

5

反応物 3

HCID 8438PiperonalHCID 14798Sodium HydroxideHCID 76622Acetopiperone

生成物 1

HCID 294346Bis(3,4-methylenedioxy)chalcone

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of piperonal (460 mg) and 3,4-methylenedioxyacetophenone (500 mg) in ethanol (20 ml) was treated with 1M NaOH solution (4 ml), then the mixture was stirred overnight. The pale yellow crystalline solid was filtered off, washed with water then cold aqueous ethanol and dried to give pure bis(3,4-methylenedioxy)chalcone DC-0006B (476 mg, 53%).

後処理

  1. filtrationThe pale yellow crystalline solid was filtered off
  2. washwashed with water
  3. dry with materialcold aqueous ethanol and dried

出典と根拠

ORDレコード
ord-6e2fb4f5e95948368cd6489babc13cc7
出典データセット
uspto-grants-2012_04
特許番号
US08163957B2

関連ノート

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