2-Bromo-1-(2-chloro-4-methoxyphenyl)-propan-1-one → 4-(2-Chloro-4-methoxyphenyl)-5-methyl-2-[N-(2-methoxy-5-nitrophenyl)-N-propylamino]thiazole

HRID 1698873

反応式

HRID 1698873 の反応式
Br[CH:2]([CH3:14])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:6]=1[Cl:13])=O.[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[CH:19][C:18]=1[N:26]([CH2:30][CH2:31][CH3:32])[C:27]([NH2:29])=[S:28]>>[Cl:13][C:6]1[CH:7]=[C:8]([O:11][CH3:12])[CH:9]=[CH:10][C:5]=1[C:3]1[N:29]=[C:27]([N:26]([C:18]2[CH:19]=[C:20]([N+:23]([O-:25])=[O:24])[CH:21]=[CH:22][C:17]=2[O:16][CH3:15])[CH2:30][CH2:31][CH3:32])[S:28][C:2]=1[CH3:14]

参加物

3

反応物 2

HCID 110549852-Bromo-1-(2-chloro-4-methoxyphenyl)-propan-1-one2 回HCID 18322274N-(2-methoxy-5-nitrophenyl)-N-propylthiourea

生成物 1

HCID 183222314-(2-Chloro-4-methoxyphenyl)-5-methyl-2-[N-(2-methoxy-5-nitrophenyl)-N-propylamino]thiazole

実験手順

By carrying out the procedure according to EXAMPLE 12 and by using 2-bromo-1-(2-chloro-4-methoxyphenyl)propan-1-one (Compound 1-2) and N-(2-methoxy-5-nitrophenyl)-N-propylthiourea, the expected product is obtained in the form of a powder; m.p.=97° C.

出典と根拠

ORDレコード
ord-95f350ebc1a14332bd49e1bc0e4ce37f
出典データセット
uspto-grants-2002_02
特許番号
US06344470B1

関連ノート

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