Thionyl Chloride → HCID 20347860、化合物

HRID 1701351ノート

反応式

HRID 1701351 の反応式
S(Cl)([Cl:3])=O.[C:5]([C:7]1[C:8]([CH3:16])=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10](O)=[O:11])#[N:6]>>[C:5]([C:7]1[C:8]([CH3:16])=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([Cl:3])=[O:11])#[N:6]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 233592293-Cyano-2-methylbenzoic acid

生成物 1

HCID 20347860HCID 20347860、化合物

実験手順

75 cc of thionyl chloride and 30 g of 3-cyano-2-methyl-benzoic acid [prepared by process in C. R. Acad. Sci., Vol. 235(1952), p. 1660] were refluxed for 11/2 hours and after cooling, excess thionyl chloride was removed under reduced pressure. The last traces of thionyl chloride were removed by addition of benzene and distillation under reduced pressure. The residue was purified by rectification under reduced pressure to obtain 27.4 g of 3-cyano-2-methyl-benzoyl chloride in the form of colorless crystals melting at 62° C.

後処理

  1. temperatureafter cooling
  2. customexcess thionyl chloride was removed under reduced pressure
  3. customThe last traces of thionyl chloride were removed by addition of benzene and distillation under reduced pressure
  4. customThe residue was purified by rectification under reduced pressure

出典と根拠

ORDレコード
ord-bea1d8e8a9cc424cbcc478e2bc6662ef
出典データセット
uspto-grants-1980_03
特許番号
US04192890

反応ノート

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