化工社化工社 化学情報印刷レポート · 研究参考用
Thiophenol → 1-(4-Chlorophenyl)-4,4-dimethyl-1-phenylthiopentan-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiophenol | HCID 7969 | — |
| 反応物 | 5-(4-Chlorophenyl)-2,2-dimethylpent-4-en-3-one | HCID 306049 | — |
| 触媒 | Triethylamine | HCID 8471 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1-(4-Chlorophenyl)-4,4-dimethyl-1-phenylthiopentan-3-one | HCID 13048711 | — |
反応手順
To a mixture of 4-chlorobenzalpinacolone (22.3 g), triethylamine (5 drops) and ethanol (250 ml) was added thiophenol (12 g) and the mixture was kept to 70° C. for 4 hours. After ice-cooling, the resulted precipitates were collected by filtration, washed with cold ethanol and dried to give white crystals of the captioned compound (29 g; 84%). m.p. 127°-128° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04379921 |
| 出典データセット | uspto-grants-1983_04 |
| ORD ID | ord-3087f43cde624e5581c37b3a4306d362 |
| 出典メモ | uspto-grants-1983_04 |