tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate → tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate

HRID 1702205ノート

反応式

HRID 1702205 の反応式
[CH2:1]([N:3]1[CH2:7][C@@H:6]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[N:5](C(OCC2C=CC=CC=2)=O)[C:4]1=[O:25])[CH3:2]>[Pd].CO>[CH2:1]([N:3]1[CH2:7][C@@H:6]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[NH:5][C:4]1=[O:25])[CH3:2]

参加物

4

反応物 1

HCID 13053979tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate

生成物 1

HCID 13053981tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate収率 96.9%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

4.2 g of tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 0.1 g of palladium-black and 100 ml of methanol are treated in the same manner as described in Example 1-(3). 2.5 g of tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate are thereby obtained as colorless crystals. Yield: 96.9% M.p. 86°-87° C.

出典と根拠

ORDレコード
ord-8bf79eef61a34ab79c62cc613db8a0a3
出典データセット
uspto-grants-1983_04
特許番号
US04380644

反応ノート

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