tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate → tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylate

HRID 1702209ノート

反応式

HRID 1702209 の反応式
[CH2:1]([N:5]1[CH2:9][C@@H:8]([C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[N:7](C(OCC2C=CC=CC=2)=O)[C:6]1=[O:27])[CH2:2][CH2:3][CH3:4]>[Pd].CO>[CH2:1]([N:5]1[CH2:9][C@@H:8]([C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[NH:7][C:6]1=[O:27])[CH2:2][CH2:3][CH3:4]

参加物

4

反応物 1

HCID 56608950tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate

生成物 1

HCID 86738844tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylate収率 88.1%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

6.7 g of tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 0.1 g of palladium-black and 200 ml of methanol are treated in the same manner as described in Example 1-(3). 3.8 g of tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylate are obtained as colorless syrup. Yield: 88.1%

出典と根拠

ORDレコード
ord-bca6784ec2e346c2ae3eaeda8b3b0884
出典データセット
uspto-grants-1983_04
特許番号
US04380644

反応ノート

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