Dimethylamine → 4-Dimethylaminomethyl-2-hydroxymethylthiazole
反応式
CNC.BrC1SC=C(CCl)N=1.Br[C:13]1[S:14][CH:15]=[C:16]([CH2:18][N:19]([CH3:21])[CH3:20])[N:17]=1.[CH2:22]=[O:23]>C(O)C>[CH3:20][N:19]([CH2:18][C:16]1[N:17]=[C:13]([CH2:22][OH:23])[S:14][CH:15]=1)[CH3:21]参加物
6
実験手順
An ethanol solution of dimethylamine is reacted with 2-bromo-4-chloromethylthiazole, prepared according to reference (4) above, and the resultant 2-bromo-4-dimethylaminomethylthiazole is treated with a strong base and formaldehyde according to the general procedure described in Acta. Chem. Scand., 20, 2649 (1966), to give the desired 4-dimethylaminomethyl-2-hydroxymethylthiazole.
後処理
- customprepared
出典と根拠
- ORDレコード
- ord-2d3e376fc09f44faa2b594b8138eef96
- 出典データセット
- uspto-grants-1983_04
- 特許番号
- US04380638
反応ノート
読み込み中…