Thionyl Chloride → alpha-Ethyl-4-(2-methylpropyl)benzeneacetyl chloride

HRID 1702468ノート

反応式

HRID 1702468 の反応式
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]([CH2:15][CH3:16])[C:12](O)=[O:13])=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]([CH2:15][CH3:16])[C:12]([Cl:19])=[O:13])=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 41643Butibufen

生成物 1

HCID 6454130alpha-Ethyl-4-(2-methylpropyl)benzeneacetyl chloride収率 98.1%

実験手順

110 g of 2-(4-isobutylphenyl)butyric acid and 89 g of thionyl chloride are heated on a water bath until the gas evolution ceases. An excess of thionyl chloride is removed by distillation, A residue of 117 g of 2-(4-isobutylphenyl)butyric chloride is obtained.

後処理

  1. customAn excess of thionyl chloride is removed by distillation

出典と根拠

ORDレコード
ord-5c56c0aa59364e53800091701c24cecd
出典データセット
uspto-grants-1983_04
特許番号
US04381313

反応ノート

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