Carbon Dioxide → Methyl[2-(phenylamino)ethyl]amine

HRID 1702492

反応式

HRID 1702492 の反応式
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:9][N:10]1[CH2:14][CH2:13]OC1=O.COCCOCCO.C(=O)=O>>[CH3:9][NH:10][CH2:14][CH2:13][NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

参加物

5

反応物 4

HCID 280Carbon DioxideHCID 8134Diethylene Glycol Monomethyl EtherHCID 8870Benzenamine hydrochloride (1:1)HCID 298312-Oxazolidinone, 3-methyl-

生成物 1

HCID 10582940Methyl[2-(phenylamino)ethyl]amine

反応条件

温度
170 °C

実験手順

A mixture of aniline hydrochloride (13.0 g, 0.10 mole), 3-methyl-2-oxazolidinone (11.0 g, 0.109 mole) and 35 ml of 2-(2-methoxyethoxy)ethanol was heated to 170° C. in an oil bath. The reaction mixture became homogenous and carbon dioxide evolution occurred on heating. After 17 hours, the reaction was allowed to cool to room temperature. After a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm), an 81 percent distilled yield of the product was obtained as a clear liquid. Product confirmation was made by the use of spectra evidence.

後処理

  1. temperatureon heating
  2. temperatureto cool to room temperature
  3. distillationAfter a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm)
  4. distillationan 81 percent distilled yield of the product
  5. customwas obtained as a clear liquid

出典と根拠

ORDレコード
ord-b4402926e87e4dc68f87a8052c946b9d
出典データセット
uspto-grants-1983_04
特許番号
US04381401

関連ノート

読み込み中…