Thionyl Chloride → HCID 178479468、化合物

HRID 1702609

反応式

HRID 1702609 の反応式
[ClH:1].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([OH:15])=O)[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4].S(Cl)([Cl:18])=O>>[ClH:18].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([Cl:1])=[O:15])[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 178479474HCID 178479474、化合物

生成物 1

HCID 178479468HCID 178479468、化合物

実験手順

A suspension of trans-4-guanidinomethylcyclohexanecarboxylic acid hydrochloride (1.2 g) and thionyl chloride (15 ml) was stirred at room temperature for 3 hours. Thereafter, excess thionyl chloride was removed by distillation under reduced pressure. The residue was washed with anhydrous ethyl ether to obtain trans-4-guanidinomethylcyclohexanecarboxylic acid chloride hydrochloride (1.2 g) as colorless powder.

後処理

  1. customThereafter, excess thionyl chloride was removed by distillation under reduced pressure
  2. washThe residue was washed with anhydrous ethyl ether

出典と根拠

ORDレコード
ord-d9af0aa0853d4105a0fad7c3b8b7641c
出典データセット
uspto-grants-1982_09
特許番号
US04348410

関連ノート

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