2-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate → 2-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

HRID 1702685ノート

反応式

HRID 1702685 の反応式
[CH2:1]([NH:17][C:18]1[CH:40]=[CH:39][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]2[CH2:32][O:31]C(C3C=CC=CC=3)[O:29][CH2:28]2)=[O:25])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[H][H]>[Pd].C(O)(=O)C>[CH2:1]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]([CH2:28][OH:29])[CH2:32][OH:31])=[O:25])=[CH:39][CH:40]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

参加物

5

反応物 2

HCID 536327232-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamateHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 540874802-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

A mixture of 2-phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate, 10% palladium-on-carbon and acetic acid is treated with hydrogen in a Parr apparatus at room temperature until hydrogen uptake ceases. The mixture is filtered and the filtrate is evaporated. Recrystallization of the residue from chloroform provides the title compound.

後処理

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated
  3. customRecrystallization of the residue from chloroform

出典と根拠

ORDレコード
ord-725f4360b40c430493054031178b1f00
出典データセット
uspto-grants-1982_09
特許番号
US04348399

反応ノート

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