Methyl iodide → 4-(Methoxycarbonyl)-1-methylpyridin-1-ium iodide
反応式
[C:1]([O:9][CH3:10])(=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH3:11][I:12]>CO>[I-:12].[CH3:10][O:9][C:1]([C:2]1[CH:7]=[CH:6][N+:5]([CH3:11])=[CH:4][CH:3]=1)=[O:8]参加物
4
実験手順
700 g of methyl isonicotinate and 1.4 kg of methyl iodide were admixed in 2.0 liters of methanol and the resultant solution was stirred and refluxed for 5 hours. After cooling, the mixture was filtered off and the product was washed with ether and dried to obtain 1.385 kg of 4-methoxycarbonyl-1-methylpyridinium iodide (97.2% yield).
後処理
- temperaturerefluxed for 5 hours
- temperatureAfter cooling
- filtrationthe mixture was filtered off
- washthe product was washed with ether
- customdried
出典と根拠
- ORDレコード
- ord-7233c854730d4f9eb2de66fb6d0e1e1a
- 出典データセット
- uspto-grants-1982_09
- 特許番号
- US04350697
反応ノート
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