Nitric Acid → 5-Methyl-2-n-propyl-4-imidazolecarboxaldehyde
反応式
[CH3:1][C:2]1[NH:6][C:5]([CH2:7][CH2:8][CH3:9])=[N:4][C:3]=1[CH2:10][OH:11].[N+]([O-])(O)=O>>[CH3:1][C:2]1[NH:6][C:5]([CH2:7][CH2:8][CH3:9])=[N:4][C:3]=1[CH:10]=[O:11]参加物
3
実験手順
An 80 gm. portion of 5-methyl-2-n-propyl-4-imidazolemethanol is oxidized with 67.3 ml. of concentrated HNO3. A second portion of 101.4 gm. of the above compound is oxidized with 77 ml. of the acid. The reaction mixtures are combined, neutralized and worked up as in Example 25, giving the desired product, m.p. 126°-129° C.
後処理
- customThe reaction mixtures
出典と根拠
- ORDレコード
- ord-119bffd7f1ac4d869fe4c2608d56b312
- 出典データセット
- uspto-grants-1978_11
- 特許番号
- US04124766
反応ノート
読み込み中…