Hydrogen Bromide → HCID 86736145、化合物
反応式
[I:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:12])[CH2:9][CH2:10]O)=[CH:4][CH:3]=1.Br.NC(N)=[S:16]>O>[I:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:12])[CH2:9][CH2:10][SH:16])=[CH:4][CH:3]=1参加物
5
実験手順
70 g of 3-(p-iodophenyl) butanol was combined in solution with 138 g of hydrobromic acid (48%) and 20 g thiourea in 100 ml of water and the thiol product vacuum distilled at 126° and 0.18 mm Hg. A 41% yield of 3-(p-Iodophenyl) butane thiol was confirmed having a refractive index of n25D = 1.6071 and nmr, ir and gc readings commensurate with the structure of the desired product.
後処理
- distillationthe thiol product vacuum distilled at 126°
出典と根拠
- ORDレコード
- ord-a570eb0d6d32463ab7ca54be87b9cf08
- 出典データセット
- uspto-grants-1978_11
- 特許番号
- US04125554
反応ノート
読み込み中…