Nitric Acid → 3-(3-Nitrobenzoyl)acrylic acid

HRID 1704711ノート

反応式

HRID 1704711 の反応式
[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:14]([O-])([OH:16])=[O:15]>>[N+:14]([C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])=[O:8])([O-:16])=[O:15]

参加物

3

反応物 2

HCID 944Nitric AcidHCID 94714Beta-benzoylacrylic acid

生成物 1

HCID 2357513-(3-Nitrobenzoyl)acrylic acid

実験手順

22g of finely powdered 3-benzoylacrylic acid was added in 1-gram portions to 11 g of stirred fuming (90%) nitric acid at -5° over a 30 minute period, the mixture being allowed to heat to 0°. Then the temperature of the mixture was allowed to rise to 2° and held until a clear solution was obtained. The mixture then was poured on ice, and the solid which formed was filtered, washed with water, dried (MgSO4) and recrystallized from ethanol to give 3-(3-nitrobenzoyl)acrylic acid (8A), m.p.: 199°-201°.

後処理

  1. temperatureto heat to 0°
  2. customto rise to 2°
  3. customwas obtained
  4. additionThe mixture then was poured on ice
  5. customthe solid which formed
  6. filtrationwas filtered
  7. washwashed with water
  8. dry with materialdried (MgSO4)
  9. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-952b487f6c904960a2f973cab219e4ea
出典データセット
uspto-grants-1978_11
特許番号
US04127656

反応ノート

読み込み中…