Benzoyl chloride → 8-Benzoyl-2-methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo-[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one

HRID 1704838ノート

反応式

HRID 1704838 の反応式
[CH3:1][C:2]1[CH:24]=[C:5]2[N:6]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:7](=[O:17])[C:8]3[CH:13]=[N:12][C:11]4[NH:14][N:15]=[CH:16][C:10]=4[C:9]=3[N:4]2[N:3]=1.[C:25](Cl)(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>N1C=CC=CC=1>[C:25]([N:14]1[C:11]2[N:12]=[CH:13][C:8]3[C:7](=[O:17])[N:6]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[C:5]4[N:4]([N:3]=[C:2]([CH3:1])[CH:24]=4)[C:9]=3[C:10]=2[CH:16]=[N:15]1)(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

参加物

4

反応物 2

HCID 7412Benzoyl chlorideHCID 227574532-Methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one

生成物 1

HCID 227574668-Benzoyl-2-methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo-[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

0.01 mol. of 2-methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one and 0.02 mol. of benzoyl chloride are stirred overnight in 50 ml. of dry pyridine at room temperature. On addition of 50 ml. of water, 8-benzoyl-2-methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one is filtered off.

後処理

  1. customat room temperature
  2. additionOn addition of 50 ml
  3. filtrationof water, 8-benzoyl-2-methyl-4-phenyl-4H-pyrazolo[1,5-a]pyrazolo4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one is filtered off

出典と根拠

ORDレコード
ord-50fd8fe98e874ca584909cbcf7dee55c
出典データセット
uspto-grants-1978_11
特許番号
US04127657

反応ノート

読み込み中…