Ethyl isocyanate → HCID 13864336、化合物

HRID 1708906ノート

反応式

HRID 1708906 の反応式
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.C1COCC1.[CH2:17]([N:19]=[C:20]=[O:21])[CH3:18]>CCOCC>[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH:9][C:20]([NH:19][CH2:17][CH3:18])=[O:21])=[O:7])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 8022Ethyl isocyanateHCID 8028TetrahydrofuranHCID 108164-Chlorobenzohydrazide

生成物 1

HCID 13864336HCID 13864336、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A stirred suspension of 4-chlorobenzoic acid, hydrazide (17.1 g, 1.00×10-1 mole), and THF (425 ml) was warmed until homogeneous, at which time ethyl isocyanate (8.7 ml, 1.1× 0-1 mole) was added via syringe. A precipitate soon formed. After stirring overnight the reaction was diluted with Et2O and the precipitate was collected by filtration affording a colorless powder: 23.7 g (98%). Crystallization from ethanol gave a colorless solid: 21.4 g (88%), mp 237°-239°.

後処理

  1. additionwas added via syringe
  2. customA precipitate soon formed
  3. filtrationthe precipitate was collected by filtration
  4. customaffording a colorless powder
  5. customCrystallization from ethanol
  6. customgave a colorless solid

出典と根拠

ORDレコード
ord-e71c439d90a844dda40fb9773a12642f
出典データセット
uspto-grants-1990_08
特許番号
US04946856

反応ノート

読み込み中…