Ethylene Glycol → Octanoic Acid

HRID 1709721

反応式

HRID 1709721 の反応式
[C:1]([O:10][CH2:11][CH2:12][OH:13])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:14]([OH:23])(=[O:22])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21].C(O)CO>>[C:1]([O:10][CH2:11][CH2:12][O:13][C:14](=[O:22])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:14]([OH:23])(=[O:22])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

参加物

5

反応物 3

HCID 174Ethylene GlycolHCID 379Octanoic AcidHCID 170609Polyethylene glycol monocaprylate

生成物 2

HCID 379Octanoic Acid収率 21%HCID 3093Dioctanoyl ethylene glycol

実験手順

Three fractions containing 68.6 to 97.8% of 2-hydroxyethyl caprylate were obtained by heating caprylic acid (1.25 mol; 180 g) with ethylene glycol (8.27 mol; 513.5 g) to boiling temperature for 5 hours and gradual distillation; the overall yield of 2-hydroxyethyl caprylate was 61.3%. In addition to 2-hydroxyethyl caprylate, ethylene dicaprylate was formed from 21% of caprylic acid. In a similar experiment, the reaction mixture after 7 hours of heating was first extracted with benzene and the benzene extract with water, instead of direct distillation. Caprylic acid was consumed in 60.6% for 2-hydroxyethyl caprylate, whereas ethylene dicaprylate resulted from 21.5% of acid; distillation gave fractions of raw product containing 97.6 to 98.5% of 2-hydroxyethyl caprylate. Further procedure was carried out according to example 1.

後処理

  1. customwere obtained
  2. customfor 5 hours
  3. distillationgradual distillation
  4. additionIn addition to 2-hydroxyethyl caprylate

出典と根拠

ORDレコード
ord-027b3f116ef44e70936b94598558cb50
出典データセット
uspto-grants-1990_08
特許番号
US04950733

関連ノート

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