HCID 86744189、化合物 → Pirazolac

HRID 1710199ノート

反応式

HRID 1710199 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[C:10]([CH2:20][C:21]([O-:23])=[O:22])=[N:9]2)=[CH:4][CH:3]=1>FC(F)(F)C(O)=O>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[C:10]([CH2:20][C:21]([OH:23])=[O:22])=[N:9]2)=[CH:6][CH:7]=1

参加物

3

反応物 1

HCID 86744189HCID 86744189、化合物

生成物 1

HCID 51222Pirazolac

試薬・触媒・溶媒 1

HCID 6422Trifluoroacetic acid溶媒

実験手順

1,49 Grams of the ester prepared according to (a) are stirred in 30 ml of trifluoroacetic acid, at room temperature. The hydrolysis is followed by TLC; at the end the excess of CF3 --COOH is evaporated in vacuo and the residue is crystallized from acetic acid/ethanol. The title product is identical with a sample prepared according to EP 54812.

後処理

  1. customat the end the excess of CF3 --COOH is evaporated in vacuo
  2. customthe residue is crystallized from acetic acid/ethanol
  3. customprepared

出典と根拠

ORDレコード
ord-937afe83f5454494b6f401f826828272
出典データセット
uspto-grants-1990_08
特許番号
US04952702

反応ノート

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