Methyl iodide → HCID 178503353、化合物
反応式
[CH3:1][I:2].[Cl:3][C:4]1[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]2[C:5]=1[CH:6]([CH3:16])[NH:7][C:8](=[S:15])[NH:9]2>CC(C)=O.C(OCC)C>[IH:2].[Cl:3][C:4]1[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]2[C:5]=1[CH:6]([CH3:16])[NH:7][C:8]([S:15][CH3:1])=[N:9]2参加物
5
実験手順
Methyl iodide (0.73 ml, 11.7 mmol) was added to a suspension of 5,8-dichloro-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (0.96 g, 3.9 mmol) in acetone (12 ml), and the mixture was stirred at room temperature overnight. The reaction was diluted with diethyl ether, and the precipitated product (1.31 g, 86%) was isolated by filtration as a white solid.
出典と根拠
- ORDレコード
- ord-dce822a163894ec5af59f7c95825da56
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07790732B2
反応ノート
読み込み中…